Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
3. Extensions to Mendelian Inheritance
Understanding Independent Assortment
Problem 3b
Textbook Question
A pure-breeding tall plant producing oval fruit as described in Problem 2 is crossed to a pure-breeding short plant producing round fruit.
If the F₁ identified in part (a) are crossed to one another, what proportion of the F₂ are expected to be short and produce round fruit? What proportion are expected to be tall and produce round fruit?

1
Determine the genotypes of the pure-breeding parents. A pure-breeding tall plant producing oval fruit would have the genotype TT for tallness and OO for oval fruit. A pure-breeding short plant producing round fruit would have the genotype tt for shortness and RR for round fruit.
Determine the genotype of the F₁ offspring. Since the parents are homozygous for their respective traits, the F₁ offspring will inherit one allele from each parent. The F₁ genotype will be Tt for height and OR for fruit shape.
Set up a Punnett square for the F₁ cross (Tt × Tt for height and OR × OR for fruit shape). This will allow you to determine the genotypic and phenotypic ratios in the F₂ generation. For height, the possible genotypes are TT, Tt, and tt. For fruit shape, the possible genotypes are OO, OR, and RR.
Identify the phenotypes corresponding to each genotype. For height, TT and Tt result in tall plants, while tt results in short plants. For fruit shape, OO results in oval fruit, OR results in oval fruit (dominant), and RR results in round fruit.
Calculate the proportion of F₂ offspring that are short and produce round fruit (ttRR) and the proportion that are tall and produce round fruit (TtRR or TTRR). Multiply the probabilities for height and fruit shape to find the final proportions for each phenotype.

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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Mendelian Genetics
Mendelian genetics is the study of how traits are inherited through generations, based on the principles established by Gregor Mendel. It involves understanding dominant and recessive alleles, where dominant traits mask the expression of recessive ones. In this scenario, the tall plant and round fruit traits are likely dominant, while short plants and oval fruit traits are recessive.
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Descriptive Genetics
Punnett Square
A Punnett square is a diagram used to predict the genotypes and phenotypes of offspring from a genetic cross. By organizing the alleles of the parent plants, it allows for a visual representation of the possible combinations in the F₂ generation. This tool is essential for determining the expected proportions of traits, such as height and fruit shape, in the offspring.
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Chi Square Analysis
Phenotypic Ratios
Phenotypic ratios refer to the relative frequencies of different phenotypes in the offspring resulting from a genetic cross. In this case, the expected proportions of short and round fruit plants can be calculated based on the genotypes of the F₁ generation. Understanding these ratios helps in predicting the likelihood of specific traits appearing in the F₂ generation.
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Mutations and Phenotypes
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Related Practice
Multiple Choice
What is the significance of the last triplet (taa) in a genetic sequence?
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