Table of contents

1. Introduction to Genetics51m
2. Mendel's Laws of Inheritance3h 37m
3. Extensions to Mendelian Inheritance2h 41m
4. Genetic Mapping and Linkage2h 28m
5. Genetics of Bacteria and Viruses1h 21m
6. Chromosomal Variation1h 48m
7. DNA and Chromosome Structure56m
8. DNA Replication1h 10m
9. Mitosis and Meiosis1h 34m
10. Transcription1h 0m
11. Translation58m
12. Gene Regulation in Prokaryotes1h 19m
13. Gene Regulation in Eukaryotes44m
14. Genetic Control of Development44m
15. Genomes and Genomics1h 50m
16. Transposable Elements47m
17. Mutation, Repair, and Recombination1h 6m
18. Molecular Genetic Tools19m
- Genetic Cloning
  9m
- Methods for Analyzing DNA
  9m
19. Cancer Genetics29m
- Overview of Cancer
  21m
- Cancer Mutations
  7m
20. Quantitative Genetics1h 26m
21. Population Genetics50m
- Hardy Weinberg
  19m
- Allelic Frequency Changes
  31m
22. Evolutionary Genetics29m

3. Extensions to Mendelian Inheritance

Overview of interacting Genes

Genetics

3. Extensions to Mendelian Inheritance

Overview of interacting Genes

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2:04 minutes

Problem 7c

Textbook Question

Provide a definition and an example for each of the following terms:
Multifactorial inheritance

Verified step by step guidance

Understand the term 'multifactorial inheritance': This refers to a pattern of inheritance where a trait or disorder is determined by the combined effects of multiple genes (polygenic inheritance) and environmental factors. It is not solely controlled by a single gene.

Provide a clear definition: Multifactorial inheritance describes traits or conditions that result from the interaction of multiple genetic factors and environmental influences. These traits do not follow simple Mendelian inheritance patterns.

Explain the role of genes and environment: In multifactorial inheritance, genetic predisposition interacts with environmental factors such as diet, lifestyle, or exposure to certain chemicals, which collectively influence the expression of the trait.

Give an example: A common example of multifactorial inheritance is height. Height is influenced by multiple genes as well as environmental factors like nutrition during childhood.

Provide another example for clarity: Another example is Type 2 diabetes, which is influenced by genetic susceptibility and environmental factors such as diet, physical activity, and body weight.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Multifactorial Inheritance

Multifactorial inheritance refers to the genetic mechanism where multiple genes and environmental factors contribute to the development of a trait or disorder. Unlike single-gene traits, multifactorial traits do not follow simple Mendelian inheritance patterns. This means that the expression of these traits can vary widely among individuals, influenced by the interaction of various genetic and non-genetic factors.

Polygenic Traits

Polygenic traits are characteristics that are controlled by two or more genes, often located on different chromosomes. These traits exhibit a continuous range of phenotypes, such as height or skin color, rather than discrete categories. The cumulative effect of multiple alleles from different genes results in the variation seen in the population, making polygenic traits a key aspect of multifactorial inheritance.

Environmental Influences

Environmental influences encompass all external factors that can affect the expression of genes and the development of traits. These can include lifestyle choices, nutrition, exposure to toxins, and other social or physical conditions. In the context of multifactorial inheritance, understanding how these environmental factors interact with genetic predispositions is crucial for comprehending the complexity of certain diseases and traits.