Table of contents

1. Introduction to Genetics51m
2. Mendel's Laws of Inheritance3h 37m
3. Extensions to Mendelian Inheritance2h 41m
4. Genetic Mapping and Linkage2h 28m
5. Genetics of Bacteria and Viruses1h 21m
6. Chromosomal Variation1h 48m
7. DNA and Chromosome Structure56m
8. DNA Replication1h 10m
9. Mitosis and Meiosis1h 34m
10. Transcription1h 0m
11. Translation58m
12. Gene Regulation in Prokaryotes1h 19m
13. Gene Regulation in Eukaryotes44m
14. Genetic Control of Development44m
15. Genomes and Genomics1h 50m
16. Transposable Elements47m
17. Mutation, Repair, and Recombination1h 6m
18. Molecular Genetic Tools19m
- Genetic Cloning
  9m
- Methods for Analyzing DNA
  9m
19. Cancer Genetics29m
- Overview of Cancer
  21m
- Cancer Mutations
  7m
20. Quantitative Genetics1h 26m
21. Population Genetics50m
- Hardy Weinberg
  19m
- Allelic Frequency Changes
  31m
22. Evolutionary Genetics29m

3. Extensions to Mendelian Inheritance

Overview of interacting Genes

Genetics

3. Extensions to Mendelian Inheritance

Overview of interacting Genes

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Multiple Choice

In a typical karyotype analysis, chromosomes are visualized as tightly packed DNA. Which technique is commonly used to prepare and observe chromosomes in this way?

DNA microarray analysis

Staining with Giemsa after arresting cells in metaphase

Southern blotting

Polymerase chain reaction (PCR)

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Verified step by step guidance

Understand that karyotype analysis involves visualizing chromosomes to study their number, size, and structure.

Recognize that chromosomes are most condensed and visible during metaphase of cell division, making this the ideal stage for observation.

Learn that cells are first arrested in metaphase using chemicals like colchicine to prevent the chromosomes from separating, thus keeping them tightly packed.

Know that after arresting cells in metaphase, chromosomes are stained to enhance their visibility under a microscope. The common stain used is Giemsa, which produces characteristic banding patterns (G-banding).

Conclude that the technique combining metaphase arrest and Giemsa staining is the standard method for preparing and observing chromosomes in karyotype analysis.