A mutant strain of Salmonella bacteria carries a mutation of the rho protein that has full activity at 37°C but is completely inactivated when the mutant strain is grown at 40°C. Speculate about the kind of differences you would expect to see if you compared a broad spectrum of mRNAs from the mutant strain grown at 37°C and the same spectrum of mRNAs from the strain when grown at 40°C.
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
10. Transcription
Transcription in Prokaryotes
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Join thousands of students who trust us to help them ace their exams!Watch the first videoMultiple Choice
How do transcription and translation differ between prokaryotes and eukaryotes?
A
In prokaryotes, mRNA is extensively processed before translation.
B
In eukaryotes, translation begins before transcription is complete.
C
In eukaryotes, transcription and translation both occur in the nucleus.
D
In prokaryotes, transcription and translation can occur simultaneously in the cytoplasm.

1
Step 1: Understand the basic processes of transcription and translation. Transcription is the synthesis of RNA from a DNA template, and translation is the process where ribosomes synthesize proteins using the mRNA sequence.
Step 2: Identify the cellular locations where these processes occur in prokaryotes and eukaryotes. In prokaryotes, both transcription and translation occur in the cytoplasm because they lack a nucleus. In eukaryotes, transcription occurs in the nucleus, and translation occurs in the cytoplasm.
Step 3: Recognize the timing of transcription and translation. In prokaryotes, transcription and translation can happen simultaneously because there is no nuclear membrane separating the processes. In eukaryotes, transcription must be completed and the mRNA processed before translation begins.
Step 4: Consider mRNA processing differences. Eukaryotic mRNA undergoes extensive processing (such as 5' capping, splicing, and polyadenylation) before it exits the nucleus for translation, whereas prokaryotic mRNA is generally not processed extensively.
Step 5: Summarize the key difference: In prokaryotes, transcription and translation are coupled and occur simultaneously in the cytoplasm, while in eukaryotes, these processes are separated both spatially (nucleus vs cytoplasm) and temporally (transcription before translation).
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