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Multiple Choice
Which phase of the cell cycle occurs before meiosis begins (i.e., before meiosis I starts)?
A
Telophase II
B
Prophase I
C
Interphase (including DNA replication during S phase)
D
Metaphase I
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1
Understand the overall sequence of the cell cycle phases leading up to meiosis. The cell cycle consists of Interphase (G1, S, G2 phases) followed by the meiotic phases (Meiosis I and Meiosis II).
Recall that Interphase is the phase where the cell prepares for division by growing and replicating its DNA. Specifically, the S phase within Interphase is when DNA replication occurs.
Recognize that meiosis begins with Meiosis I, starting at Prophase I, which follows Interphase. Therefore, the phase immediately before Prophase I is Interphase.
Identify that Telophase II and Metaphase I are stages within meiosis itself, occurring after Interphase and the start of meiosis, so they cannot be the phase before meiosis begins.
Conclude that the phase before meiosis starts (before Meiosis I) is Interphase, during which DNA replication occurs to ensure each chromosome consists of two sister chromatids.