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Multiple Choice
Which of the following base compositions is possible for double-stranded DNA?
A
A = 10%, T = 40%, G = 25%, C = 25%
B
A = 30%, T = 30%, G = 20%, C = 20%
C
A = 20%, T = 20%, G = 30%, C = 40%
D
A = 35%, T = 15%, G = 25%, C = 25%
Verified step by step guidance
1
Recall Chargaff's rules, which state that in double-stranded DNA, the amount of adenine (A) equals thymine (T), and the amount of guanine (G) equals cytosine (C). This means $A = T$ and $G = C$.
Check each given base composition to see if the percentages of A and T are equal, and if the percentages of G and C are equal.
Verify that the total percentage of all four bases adds up to 100% for each option, since the sum of all nucleotide percentages must be 100%.
For each option, confirm both conditions: $A = T$, $G = C$, and $A + T + G + C = 100\%$.
Identify the option(s) that satisfy both Chargaff's rules and the total percentage requirement, which indicates a possible base composition for double-stranded DNA.