Textbook Question
It is common to study the biology and genetics of bacteria, yeast, fruit flies, and mice to understand biological and genetic processes in humans. Why do you think this is the case?
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1. Introduction to Genetics
History of Genetics
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Who was responsible for the initial base pairing experiment that provided key evidence for the structure of DNA?
A
Gregor Mendel
B
Rosalind Franklin
C
Erwin Chargaff
D
Thomas Hunt Morgan
Verified step by step guidance1
Understand the context of the question: it asks about the scientist responsible for the initial base pairing experiment that provided key evidence for the structure of DNA.
Recall the contributions of each scientist listed: Gregor Mendel is known for genetics and inheritance patterns, Rosalind Franklin for X-ray diffraction images of DNA, Thomas Hunt Morgan for chromosome theory of inheritance, and Erwin Chargaff for base pairing rules.
Focus on Erwin Chargaff's work, which involved analyzing the amounts of adenine, thymine, guanine, and cytosine in DNA and discovering that adenine pairs with thymine and guanine pairs with cytosine in roughly equal amounts.
Recognize that Chargaff's rules provided critical chemical evidence supporting the double helix model of DNA proposed by Watson and Crick.
Conclude that Erwin Chargaff was responsible for the initial base pairing experiment that provided key evidence for the structure of DNA.
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