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Multiple Choice
During mitosis, two sister chromatids are held together at the:
A
kinetochore
B
spindle fiber
C
telomere
D
centromere
Verified step by step guidance
1
Understand the structure of a chromosome during mitosis: each chromosome consists of two sister chromatids joined together.
Recall that sister chromatids are connected at a specific region called the centromere, which is crucial for their proper segregation.
Identify the role of the centromere as the attachment site for spindle fibers via the kinetochore during mitosis.
Differentiate between the terms: kinetochore (protein complex on the centromere), spindle fibers (microtubules that pull chromatids apart), and telomeres (ends of chromatids).
Conclude that the correct answer is the centromere, as it is the region where sister chromatids are held together.