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Multiple Choice
In most prokaryotic cells (bacteria and archaea), where is the cell’s chromosomal DNA primarily located?
A
Inside a membrane-bound nucleus
B
In the nucleoid region of the cytoplasm (not enclosed by a membrane)
C
Within mitochondria
D
In the rough endoplasmic reticulum
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1
Understand the structure of prokaryotic cells: Prokaryotes, such as bacteria and archaea, lack membrane-bound organelles, including a nucleus.
Recall that in eukaryotic cells, chromosomal DNA is enclosed within a membrane-bound nucleus, but this is not the case for prokaryotes.
Identify that in prokaryotes, the chromosomal DNA is located in a specific region of the cytoplasm called the nucleoid, which is not enclosed by a membrane.
Recognize that mitochondria and rough endoplasmic reticulum are organelles found in eukaryotic cells, not in prokaryotes, so DNA is not located there in prokaryotes.
Conclude that the chromosomal DNA in prokaryotic cells is primarily found in the nucleoid region of the cytoplasm, which is distinct from a membrane-bound nucleus.