Multiple Choice
Sister chromatids are attached to one another at the:
4
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3. Extensions to Mendelian Inheritance
Overview of interacting Genes
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Which of the following correctly ranks the DNA base pairs from most stable to least stable?
A
A=T > T=A > G≡C
B
A=T > G≡C
C
G≡C > A=T
D
G≡C = A=T
Verified step by step guidance1
Recall that DNA base pairs are held together by hydrogen bonds: adenine (A) pairs with thymine (T) via two hydrogen bonds, and guanine (G) pairs with cytosine (C) via three hydrogen bonds.
Understand that the stability of a base pair is largely determined by the number of hydrogen bonds; more hydrogen bonds generally mean greater stability.
Compare the base pairs: since G≡C pairs have three hydrogen bonds and A=T pairs have two, G≡C pairs are more stable than A=T pairs.
Evaluate the given options by checking if they correctly reflect the relative stability based on the number of hydrogen bonds, i.e., whether G≡C is ranked higher than A=T.
Conclude that the correct ranking from most stable to least stable is $G \equiv C > A = T$, because the triple hydrogen bond in G≡C provides greater stability than the double bond in A=T.
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