Multiple Choice
In bacterial DNA replication, what is the primary function of DNA polymerase III?
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8. DNA Replication
Overview of DNA Replication
Multiple Choice
In an overview of DNA replication, which enzyme is primarily responsible for unwinding the DNA double helix at the replication fork?
A
Primase
B
DNA ligase
C
DNA polymerase III
D
DNA helicase
Verified step by step guidance1
Understand the role of each enzyme listed in the context of DNA replication.
Recall that DNA helicase is the enzyme responsible for unwinding the DNA double helix by breaking the hydrogen bonds between the base pairs at the replication fork.
Recognize that primase synthesizes RNA primers, which are necessary for DNA polymerase to begin replication, but does not unwind DNA.
Know that DNA polymerase III is the main enzyme that adds nucleotides to the growing DNA strand but requires the DNA to be unwound first.
Identify that DNA ligase joins Okazaki fragments on the lagging strand but does not participate in unwinding the DNA.
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