Multiple Choice
Which syndrome is characterized by the presence of a single X chromosome (XO) in humans?
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3. Extensions to Mendelian Inheritance
Sex Chromosome
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Which sex chromosome genotype is associated with Jacob syndrome?
A
47,XYY
B
47,XXY
C
47,XXX
D
45,X
Verified step by step guidance1
Understand that Jacob syndrome is a chromosomal disorder involving the sex chromosomes, specifically an abnormal number of Y chromosomes in males.
Recall the normal male karyotype is 46,XY and the normal female karyotype is 46,XX.
Identify that Jacob syndrome is characterized by the presence of an extra Y chromosome, leading to a total of 47 chromosomes.
Recognize that the notation for Jacob syndrome is 47,XYY, indicating one X chromosome and two Y chromosomes.
Compare the given options to this notation to determine that 47,XYY corresponds to Jacob syndrome.
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