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Multiple Choice
In a single DNA strand, what type of bond links nucleotides together to form the sugar-phosphate backbone?
A
Covalent phosphodiester bonds between the hydroxyl of one sugar and the phosphate of the next nucleotide
B
Peptide bonds between nucleotides
C
Hydrogen bonds between complementary nitrogenous bases (A–T and G–C)
D
Ionic bonds between negatively charged phosphate groups and positively charged bases
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Verified step by step guidance
1
Identify the components of a nucleotide: a sugar (deoxyribose), a phosphate group, and a nitrogenous base.
Understand that nucleotides in a single DNA strand are linked to form a sugar-phosphate backbone.
Recognize that the bond linking nucleotides in the backbone is a covalent bond called a phosphodiester bond.
Know that this phosphodiester bond forms specifically between the 3\' hydroxyl group of one sugar and the 5\' phosphate group of the next nucleotide.
Distinguish this from other types of bonds: peptide bonds link amino acids, hydrogen bonds link complementary bases between strands, and ionic bonds are not involved in the backbone structure.