Table of contents

1. Introduction to Genetics51m
2. Mendel's Laws of Inheritance3h 37m
3. Extensions to Mendelian Inheritance2h 41m
4. Genetic Mapping and Linkage2h 28m
5. Genetics of Bacteria and Viruses1h 21m
6. Chromosomal Variation1h 48m
7. DNA and Chromosome Structure56m
8. DNA Replication1h 10m
9. Mitosis and Meiosis1h 34m
10. Transcription1h 0m
11. Translation58m
12. Gene Regulation in Prokaryotes1h 19m
13. Gene Regulation in Eukaryotes44m
14. Genetic Control of Development44m
15. Genomes and Genomics1h 50m
16. Transposable Elements47m
17. Mutation, Repair, and Recombination1h 6m
18. Molecular Genetic Tools19m
- Genetic Cloning
  9m
- Methods for Analyzing DNA
  9m
19. Cancer Genetics29m
- Overview of Cancer
  21m
- Cancer Mutations
  7m
20. Quantitative Genetics1h 26m
21. Population Genetics50m
- Hardy Weinberg
  19m
- Allelic Frequency Changes
  31m
22. Evolutionary Genetics29m

7. DNA and Chromosome Structure

DNA as the Genetic Material

Genetics

7. DNA and Chromosome Structure

DNA as the Genetic Material

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Multiple Choice

Which experiment provided the most direct evidence that DNA is the genetic material in cells?

Meselson and Stahl's experiment on DNA replication

Griffith's experiment with Streptococcus pneumoniae

Hershey and Chase's blender experiment with bacteriophages

Avery, MacLeod, and McCarty's transformation experiment

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Verified step by step guidance

Understand the context: The question asks which experiment provided the most direct evidence that DNA is the genetic material, meaning it showed that DNA, not protein or other molecules, carries genetic information.

Review Griffith's experiment: It demonstrated the phenomenon of transformation in bacteria but did not identify DNA as the transforming substance.

Consider Avery, MacLeod, and McCarty's experiment: They isolated different macromolecules from heat-killed bacteria and showed that only DNA could transform non-virulent bacteria into virulent forms, providing strong evidence that DNA is the genetic material.

Look at Hershey and Chase's blender experiment: They used bacteriophages labeled with radioactive isotopes to show that DNA, not protein, enters bacterial cells during infection, confirming DNA as the genetic material.

Compare Meselson and Stahl's experiment: It demonstrated the semi-conservative replication of DNA but did not directly prove DNA is the genetic material.