Multiple Choice
In which direction does RNA polymerase synthesize mRNA during transcription?
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10. Transcription
Overview of Transcription
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Join thousands of students who trust us to help them ace their exams!Watch the first videoMultiple Choice
Which of the following is NOT true of RNA polymerase?
A
RNA polymerase requires a primer to initiate RNA synthesis.
B
RNA polymerase uses ribonucleotides as substrates.
C
RNA polymerase unwinds the DNA double helix during transcription.
D
RNA polymerase synthesizes RNA in the 5' to 3' direction.
Verified step by step guidance1
Step 1: Understand the role of RNA polymerase in transcription. RNA polymerase is the enzyme responsible for synthesizing RNA from a DNA template.
Step 2: Recall that RNA polymerase uses ribonucleotides (ATP, UTP, CTP, GTP) as substrates to build the RNA strand complementary to the DNA template strand.
Step 3: Remember that RNA polymerase unwinds the DNA double helix locally to expose the template strand for RNA synthesis during transcription.
Step 4: Know that RNA polymerase synthesizes RNA in the 5' to 3' direction by adding nucleotides to the 3' end of the growing RNA chain.
Step 5: Recognize that unlike DNA polymerase, RNA polymerase does NOT require a primer to initiate RNA synthesis; it can start RNA synthesis de novo.
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