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Multiple Choice
What would most likely happen if a cell skipped metaphase during mitosis?
A
The nuclear envelope would fail to break down, preventing chromosome separation.
B
Sister chromatids would separate normally, but spindle fibers would not form.
C
Chromosomes would not align at the cell's equator, leading to unequal chromosome distribution in daughter cells.
D
Cytokinesis would occur before chromosome replication, resulting in cells with double the normal chromosome number.
Verified step by step guidance
1
Understand the role of metaphase in mitosis: during metaphase, chromosomes align at the cell's equator (the metaphase plate), ensuring that each daughter cell will receive an equal set of chromosomes.
Recognize that if metaphase is skipped, chromosomes will not properly align at the metaphase plate, disrupting the orderly separation process.
Recall that the spindle fibers attach to the centromeres of sister chromatids and help pull them apart during anaphase; without proper alignment, spindle fibers cannot evenly distribute chromosomes.
Consider the consequence of misaligned chromosomes: unequal distribution of chromosomes to daughter cells, which can lead to genetic imbalances.
Conclude that skipping metaphase leads to improper chromosome alignment and segregation, resulting in daughter cells with unequal chromosome numbers.