Textbook Question
Predict how the synaptic configurations of homologous pairs of chromosomes might appear when one member is normal and the other member has sustained a deletion or duplication.
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6. Chromosomal Variation
Chromosomal Rearrangements: Overview
Multiple Choice
The following picture depicts which of the following changes in chromosome structure?
A
Deletion
B
Duplication
C
Inversion
D
Translocation
Verified step by step guidance1
Step 1: Understand the types of chromosome structural changes. Deletion involves loss of a chromosome segment, duplication involves repetition of a segment, inversion involves a segment being flipped in orientation, and translocation involves segments moving between nonhomologous chromosomes.
Step 2: Identify the key feature of an inversion: a chromosome segment breaks off, flips 180 degrees, and reattaches in the reverse orientation within the same chromosome.
Step 3: Examine the picture carefully to see if a segment of the chromosome appears reversed in order but remains on the same chromosome, which is characteristic of an inversion.
Step 4: Rule out deletion if no segment is missing, duplication if no segment is repeated, and translocation if no segment has moved to a different chromosome.
Step 5: Conclude that the depicted change is an inversion because the chromosome segment is reversed in orientation but remains part of the same chromosome.
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