Table of contents

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1. Introduction to Genetics51m
2. Mendel's Laws of Inheritance3h 37m
3. Extensions to Mendelian Inheritance2h 41m
4. Genetic Mapping and Linkage2h 28m
5. Genetics of Bacteria and Viruses1h 21m
6. Chromosomal Variation1h 48m
7. DNA and Chromosome Structure56m
8. DNA Replication1h 10m
9. Mitosis and Meiosis1h 34m
10. Transcription1h 0m
11. Translation58m
12. Gene Regulation in Prokaryotes1h 19m
13. Gene Regulation in Eukaryotes44m
14. Genetic Control of Development44m
15. Genomes and Genomics1h 50m
16. Transposable Elements47m
17. Mutation, Repair, and Recombination1h 6m
18. Molecular Genetic Tools19m
- Genetic Cloning
  9m
- Methods for Analyzing DNA
  9m
19. Cancer Genetics29m
- Overview of Cancer
  21m
- Cancer Mutations
  7m
20. Quantitative Genetics1h 26m
21. Population Genetics50m
- Hardy Weinberg
  19m
- Allelic Frequency Changes
  31m
22. Evolutionary Genetics29m

3. Extensions to Mendelian Inheritance

Overview of interacting Genes

Genetics

3. Extensions to Mendelian Inheritance

Overview of interacting Genes

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Multiple Choice

Which of the following characterizes BRCA1 and BRCA2 as tumor-suppressor genes?

They encode proteins that directly activate oncogenes.

They promote cell proliferation in response to growth signals.

They are only expressed in cancerous cells.

They prevent uncontrolled cell division by repairing DNA damage.

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Verified step by step guidance

Understand the role of tumor-suppressor genes: These genes produce proteins that help regulate cell growth and division, preventing cells from dividing uncontrollably.

Recognize that BRCA1 and BRCA2 are involved in DNA repair mechanisms, specifically repairing double-strand breaks in DNA to maintain genomic stability.

Note that unlike oncogenes, which promote cell proliferation, tumor-suppressor genes like BRCA1 and BRCA2 act to prevent excessive cell division by fixing DNA damage.

Realize that BRCA1 and BRCA2 are expressed in normal cells to maintain DNA integrity, not only in cancerous cells.

Conclude that the key characteristic of BRCA1 and BRCA2 as tumor-suppressor genes is their role in preventing uncontrolled cell division through DNA repair.