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1. Introduction to Genetics51m
2. Mendel's Laws of Inheritance3h 37m
3. Extensions to Mendelian Inheritance2h 41m
4. Genetic Mapping and Linkage2h 28m
5. Genetics of Bacteria and Viruses1h 21m
6. Chromosomal Variation1h 48m
7. DNA and Chromosome Structure56m
8. DNA Replication1h 10m
9. Mitosis and Meiosis1h 34m
10. Transcription1h 0m
11. Translation58m
12. Gene Regulation in Prokaryotes1h 19m
13. Gene Regulation in Eukaryotes44m
14. Genetic Control of Development44m
15. Genomes and Genomics1h 50m
16. Transposable Elements47m
17. Mutation, Repair, and Recombination1h 6m
18. Molecular Genetic Tools19m
- Genetic Cloning
  9m
- Methods for Analyzing DNA
  9m
19. Cancer Genetics29m
- Overview of Cancer
  21m
- Cancer Mutations
  7m
20. Quantitative Genetics1h 26m
21. Population Genetics50m
- Hardy Weinberg
  19m
- Allelic Frequency Changes
  31m
22. Evolutionary Genetics29m

17. Mutation, Repair, and Recombination

DNA Repair

Genetics

17. Mutation, Repair, and Recombination

DNA Repair

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Multiple Choice

Refer to the figure. Which structure is responsible for stabilizing DNA in its single-stranded form?

Helicase

Single-strand binding proteins (SSBs)

DNA polymerase

DNA ligase

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Verified step by step guidance

Understand the context: During DNA replication, the double helix is unwound to expose single-stranded DNA (ssDNA) templates.

Identify the role of helicase: Helicase is the enzyme that unwinds the DNA helix by breaking hydrogen bonds between base pairs, creating ssDNA regions.

Recognize the problem with ssDNA: Single-stranded DNA is unstable and prone to forming secondary structures or being degraded.

Learn the function of Single-Strand Binding Proteins (SSBs): SSBs bind to the exposed ssDNA to stabilize it, preventing it from re-annealing or forming secondary structures.

Distinguish other enzymes: DNA polymerase synthesizes new DNA strands, and DNA ligase joins DNA fragments; neither stabilizes ssDNA directly.