Table of contents

1. Introduction to Genetics51m
2. Mendel's Laws of Inheritance3h 37m
3. Extensions to Mendelian Inheritance2h 41m
4. Genetic Mapping and Linkage2h 28m
5. Genetics of Bacteria and Viruses1h 21m
6. Chromosomal Variation1h 48m
7. DNA and Chromosome Structure56m
8. DNA Replication1h 10m
9. Mitosis and Meiosis1h 34m
10. Transcription1h 0m
11. Translation58m
12. Gene Regulation in Prokaryotes1h 19m
13. Gene Regulation in Eukaryotes44m
14. Genetic Control of Development44m
15. Genomes and Genomics1h 50m
16. Transposable Elements47m
17. Mutation, Repair, and Recombination1h 6m
18. Molecular Genetic Tools19m
- Genetic Cloning
  9m
- Methods for Analyzing DNA
  9m
19. Cancer Genetics29m
- Overview of Cancer
  21m
- Cancer Mutations
  7m
20. Quantitative Genetics1h 26m
21. Population Genetics50m
- Hardy Weinberg
  19m
- Allelic Frequency Changes
  31m
22. Evolutionary Genetics29m

15. Genomes and Genomics

Proteomics

Genetics

15. Genomes and Genomics

Proteomics

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1:46 minutes

Problem 20b

Textbook Question

An interactive Web site for the Human Proteome Map (HPM) is available at http://www.humanproteomemap.org. Visit this site, and then answer the question.
How many fetal tissues were analyzed?

Verified step by step guidance

Visit the Human Proteome Map website at http://www.humanproteomemap.org.

Navigate to the section of the website that provides information about fetal tissues analyzed.

Look for a summary or dataset that lists the number of fetal tissues studied. This may be under a specific tab or section such as 'Tissues' or 'Data Overview'.

Identify the specific count of fetal tissues analyzed from the provided information or dataset.

Ensure you cross-reference the data with any supplementary materials or descriptions provided on the website to confirm accuracy.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Human Proteome Map (HPM)

The Human Proteome Map (HPM) is a comprehensive resource that catalogs the proteins expressed in human tissues, providing insights into their functions and interactions. It serves as a valuable tool for researchers to understand the complexity of human biology and disease mechanisms by mapping protein expression across various tissues, including fetal tissues.

Fetal Tissues

Fetal tissues refer to the various types of biological tissues that develop during the gestation period in humans. These tissues are crucial for understanding developmental biology and can provide insights into congenital disorders and the overall growth processes. Analyzing fetal tissues helps researchers identify specific proteins that are essential during different stages of fetal development.

Interactive Web Resource

The interactive web resource for the HPM allows users to explore and visualize data related to protein expression in different human tissues. This platform provides tools for searching, filtering, and analyzing data, making it easier for researchers and students to access and interpret complex biological information. Engaging with such resources enhances understanding of proteomics and its applications in health and disease.

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Related Practice

Textbook Question

The CBF genes of Arabidopsis are induced by exposure of the plants to low temperature. How would you examine the temporal and spatial patterns of expression after induction by low temperature?

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Textbook Question

The two-hybrid method facilitates the discovery of protein–protein interactions. How does this technique work? Can you think of reasons for obtaining a false-positive result, that is, where the proteins encoded by two clones interact in the two-hybrid system but do not interact in the organism in which they naturally occur? Can you think of reasons you might obtain a false-negative result, in which the two proteins interact in vivo but fail to interact in the two-hybrid system?

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Textbook Question

Annotation of the human genome sequence reveals a discrepancy between the number of protein-coding genes and the number of predicted proteins actually expressed by the genome. Proteomic analysis indicates that human cells are capable of synthesizing more than 100,000 different proteins and perhaps three times this number. What is the discrepancy, and how can it be reconciled?

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Textbook Question

An interactive Web site for the Human Proteome Map (HPM) is available at http://www.humanproteomemap.org. Visit this site, and then answer the question.

Use the 'Query' tab and select the 'Gene family' dropdown menu to do a search on the distribution of proteins encoded by a pathway of interest to you. Search in fetal tissues, adult tissues, or both.

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Textbook Question

An interactive Web site for the Human Proteome Map (HPM) is available at http://www.humanproteomemap.org. Visit this site, and then answer the question.

How many proteins were identified in this project?

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Textbook Question

Genomic sequencing has opened the door to numerous studies that help us understand the evolutionary forces shaping the genetic makeup of organisms. Using databases containing the sequences of 25 genomes, scientists examined the relationship between GC content and global amino acid composition [Kreil, D. P., and Ouzounis, C. A. (2001) Nucl. Acids Res. 29:1608–1615]. They found that it is possible to identify thermophilic species on the basis of their amino acid composition alone, which suggests that evolution in a hot environment selects for a certain whole organism amino acid composition. In what way might evolution in extreme environments influence genome and amino acid composition? How might evolution in extreme environments influence the interpretation of genome sequence data?

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Multiple Choice

SDS-PAGE is a method used to separate proteins by which of the following characteristics?

Which of the following methods would be best to identify an amino acid sequence of a protein?

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