Horse diploid cells contain 64 chromosomes (2n=64). How many chromosomes will be present in primary oocyte cells?
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
9. Mitosis and Meiosis
Development of Animal Gametes
Problem 17
Textbook Question
During oogenesis in an animal species with a haploid number of 6, one dyad undergoes nondisjunction during meiosis II. Following the second meiotic division, this dyad ends up intact in the ovum. How many chromosomes are present in
(a) the mature ovum and
(b) the second polar body?
(c) Following fertilization by a normal sperm, what chromosome condition is created?

1
Understand the problem: The haploid number (n) is 6, meaning a normal gamete should have 6 chromosomes. Nondisjunction during meiosis II means that one dyad (a pair of sister chromatids) fails to separate, leading to an abnormal distribution of chromosomes in the resulting cells.
Determine the chromosome count in the mature ovum: Since one dyad remains intact in the ovum due to nondisjunction, the ovum will have the normal haploid number (6 chromosomes) plus one extra chromosome from the nondisjunction event. This results in 6 + 1 = 7 chromosomes in the ovum.
Determine the chromosome count in the second polar body: The second polar body will lack the chromosome that failed to separate during nondisjunction. Therefore, it will have the normal haploid number (6 chromosomes) minus one chromosome, resulting in 6 - 1 = 5 chromosomes in the second polar body.
Analyze the chromosome condition after fertilization: A normal sperm contributes the haploid number of chromosomes (6) to the ovum. Since the ovum already has 7 chromosomes due to nondisjunction, the resulting zygote will have 6 (from the sperm) + 7 (from the ovum) = 13 chromosomes. This creates a condition known as trisomy, where one chromosome is present in three copies instead of the normal two.
Summarize the outcomes: (a) The mature ovum has 7 chromosomes. (b) The second polar body has 5 chromosomes. (c) Following fertilization, the zygote has 13 chromosomes, resulting in a trisomic condition for one chromosome.

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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Meiosis and Nondisjunction
Meiosis is a specialized type of cell division that reduces the chromosome number by half, resulting in four haploid cells. Nondisjunction is an error that occurs when homologous chromosomes or sister chromatids fail to separate properly during meiosis, leading to gametes with an abnormal number of chromosomes. In this case, nondisjunction during meiosis II results in one gamete with an extra chromosome.
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Meiosis Steps
Haploid and Diploid Numbers
In sexually reproducing organisms, the haploid number (n) represents the number of chromosomes in a gamete, while the diploid number (2n) is the total number of chromosomes in somatic cells. For the species in question, the haploid number is 6, meaning that normal gametes contain 6 chromosomes. After nondisjunction, the mature ovum will have 7 chromosomes, while the second polar body will have 5.
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Diploid Genetics
Fertilization and Chromosome Condition
Fertilization occurs when a sperm cell fuses with an ovum, resulting in a zygote with a diploid chromosome number. In this scenario, the normal sperm contributes 6 chromosomes to the ovum that has 7 due to nondisjunction, leading to a zygote with 13 chromosomes. This condition is termed aneuploidy, which can result in developmental issues or genetic disorders.
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