Table of contents

1. Introduction to Genetics51m
2. Mendel's Laws of Inheritance3h 37m
3. Extensions to Mendelian Inheritance2h 41m
4. Genetic Mapping and Linkage2h 28m
5. Genetics of Bacteria and Viruses1h 21m
6. Chromosomal Variation1h 48m
7. DNA and Chromosome Structure56m
8. DNA Replication1h 10m
9. Mitosis and Meiosis1h 34m
10. Transcription1h 0m
11. Translation58m
12. Gene Regulation in Prokaryotes1h 19m
13. Gene Regulation in Eukaryotes44m
14. Genetic Control of Development44m
15. Genomes and Genomics1h 50m
16. Transposable Elements47m
17. Mutation, Repair, and Recombination1h 6m
18. Molecular Genetic Tools19m
- Genetic Cloning
  9m
- Methods for Analyzing DNA
  9m
19. Cancer Genetics29m
- Overview of Cancer
  21m
- Cancer Mutations
  7m
20. Quantitative Genetics1h 26m
21. Population Genetics50m
- Hardy Weinberg
  19m
- Allelic Frequency Changes
  31m
22. Evolutionary Genetics29m

3. Extensions to Mendelian Inheritance

Maternal Effect

Genetics

3. Extensions to Mendelian Inheritance

Maternal Effect

Previous problemNext problem

0:40 minutes

Problem 1d

Textbook Question

In the discussion, we focused on extranuclear inheritance and how traits can be determined by genetic information contained in mitochondria and chloroplasts, and we discussed how expression of maternal genotypes can affect the phenotype of an organism. At the same time, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter, what answers would you propose to the following fundamental questions?
What key observations in crosses between dextrally and sinistrally coiled snails support the explanation that this phenotype is the result of maternal-effect inheritance?

Verified step by step guidance

Understand the concept of maternal-effect inheritance: Maternal-effect inheritance occurs when the phenotype of an organism is determined by the genotype of its mother, rather than its own genotype. This is often due to substances deposited in the egg by the mother during oogenesis.

Review the phenotype of dextrally and sinistrally coiled snails: Dextrally coiled snails have shells that coil to the right, while sinistrally coiled snails have shells that coil to the left. These traits are influenced by maternal-effect inheritance.

Examine the key observation in snail crosses: When a dextral female snail is crossed with a sinistral male snail, all offspring exhibit dextral coiling, regardless of their own genotype. Conversely, when a sinistral female snail is crossed with a dextral male snail, all offspring exhibit sinistral coiling.

Analyze the reasoning behind maternal-effect inheritance: The phenotype of the offspring is determined by the genotype of the mother because the mother’s genotype influences the cytoplasmic factors deposited in the egg, which direct early development and determine coiling direction.

Conclude with the evidence supporting maternal-effect inheritance: The consistent correlation between the mother’s genotype and the offspring’s phenotype, regardless of the offspring’s own genotype, strongly supports the explanation that coiling direction in snails is a result of maternal-effect inheritance.

Verified video answer for a similar problem:

This video solution was recommended by our tutors as helpful for the problem above

Video duration:

40s

Play a video:

Was this helpful?

Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Extranuclear Inheritance

Extranuclear inheritance refers to the transmission of genetic material that occurs outside the nucleus, primarily through organelles like mitochondria and chloroplasts. This type of inheritance is distinct from Mendelian inheritance, as it does not follow the typical patterns of segregation and independent assortment. In organisms, traits influenced by extranuclear genes can be inherited maternally, meaning they are passed from mother to offspring through the cytoplasm of the egg.

Maternal Effect

Maternal effect is a phenomenon where the genotype of the mother directly influences the phenotype of her offspring, regardless of the offspring's own genotype. This occurs because the mother provides cytoplasmic factors, such as RNAs and proteins, that affect early development. In the case of the coiling direction in snails, the maternal genotype determines the phenotype of the offspring, illustrating how maternal contributions can shape traits.

Phenotypic Expression in Snails

The phenotypic expression of traits in organisms, such as the coiling direction of snails, can be influenced by genetic factors from both nuclear and extranuclear sources. In dextrally and sinistrally coiled snails, the observed phenotypes can be traced back to the maternal genotype, which provides the necessary cytoplasmic determinants. Key observations in crosses, such as consistent coiling direction in offspring regardless of paternal genotype, support the concept of maternal-effect inheritance.

Watch next

Master Maternal Effect with a bite sized video explanation from Kylia

Start learning