Describe three major goals of the Human Genome Project.

Using the data in Table B, calculate the average number of kilobase (kb) pairs per centimorgan in the six multicellular eukaryotic organisms. How would this information influence strategies to clone genes known only by a mutant phenotype in these organisms?

Diseases and conditions on the RUSP list are tested on every newborn infant, and if the baby has one of the conditions, the parents are immediately informed. What kind of information and counseling should be provided to the parents along with the diagnosis?

Diagram the mechanism by which CRISPR–Cas functions in the immune system of bacteria and archaea.

Describe how CRISPR–Cas has been modified to create a genome-editing tool.

You have identified a gene encoding the protein involved in the rate-limiting step in vitamin E biosynthesis. How would you create a transgenic plant producing large quantities of vitamin E in its seeds?

Describe the human genome in terms of genome size, the percentage of the genome that codes for proteins, how much is composed of repetitive sequences, and how many genes it contains. Describe two other features of the human genome.

You have identified a recessive mutation that alters bristle patterning in Drosophila and have used recombinant DNA technology to identify a genomic clone that you believe harbors the gene. How would you demonstrate that your gene is on the genomic clone?

The Human Genome Project has demonstrated that in humans of all races and nationalities approximately 99.9 percent of the genome sequence is the same, yet different individuals can be identified by DNA fingerprinting techniques. What is one primary variation in the human genome that can be used to distinguish different individuals? Briefly explain your answer.