Draw all possible conclusions concerning the mode of inheritance of the trait portrayed in the following limited pedigree.

The accompanying pedigree shows the transmission of a phenotypic character. Using B to represent a dominant allele and b to represent a recessive allele,

Give the genotype(s) possible for each member of the family, assuming the trait is autosomal dominant. 

Draw all possible conclusions concerning the mode of inheritance of the trait portrayed in the following limited pedigree.

Draw all possible conclusions concerning the mode of inheritance of the trait portrayed in the following limited pedigree.

Draw all possible conclusions concerning the mode of inheritance of the trait portrayed in the following limited pedigree.

A 'wrongful birth' case was recently brought before a court in which a child with Smith–Lemli–Opitz syndrome was born to apparently healthy parents. This syndrome is characterized by a cluster of birth defects including cleft palate, and an array of problems with the reproductive and urinary organs. Originally considered by their physician as having a nongenetic basis, the parents decided to have another child, who was also born with Smith–Lemli–Opitz syndrome. In the role of a genetic counselor, instruct the court about what occurred, including the probability of the parents having two affected offspring, knowing that the disorder is inherited as a recessive trait.

A 'wrongful birth' case was recently brought before a court in which a child with Smith–Lemli–Opitz syndrome was born to apparently healthy parents. This syndrome is characterized by a cluster of birth defects including cleft palate, and an array of problems with the reproductive and urinary organs. Originally considered by their physician as having a nongenetic basis, the parents decided to have another child, who was also born with Smith–Lemli–Opitz syndrome. In the role of a genetic counselor, instruct the court about what occurred, including the probability of the parents having two affected offspring, knowing that the disorder is inherited as a recessive trait. Draw a pedigree of the families of this couple, showing the relevant individuals.

Consider the three pedigrees below, all involving a single human trait.

Given your conclusions in part (a), indicate the genotype of the following individuals: II-1, II-6, II-9 If more than one possibility applies, list all possibilities. Use the symbols A and a for the genotypes.