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Multiple Choice
Which of the following terms is associated with closed chromatin?
A
CpG islands
B
Heterochromatin
C
Methylation
D
Euchromatin
Verified step by step guidance
1
Understand the concept of chromatin: Chromatin is a complex of DNA and proteins found in the nucleus of eukaryotic cells. It can exist in two forms: euchromatin and heterochromatin.
Define euchromatin: Euchromatin is a less condensed form of chromatin that is generally associated with active transcription. It is often referred to as 'open' chromatin.
Define heterochromatin: Heterochromatin is a tightly packed form of DNA, which is transcriptionally inactive. It is often referred to as 'closed' chromatin.
Explain the role of methylation: DNA methylation is a biochemical process that adds a methyl group to the DNA molecule, often at CpG sites. This process is associated with the repression of gene expression and is a key feature of heterochromatin.
Connect the terms: The term 'heterochromatin' is associated with closed chromatin due to its tightly packed structure and transcriptional inactivity, often maintained by DNA methylation.