Textbook Question
An animal heterozygous for a reciprocal balanced translocation has the following chromosomes:
MN • OPQRST
MN • OPQRjkl
cdef • ghijkl
cdef • ghiST
Diagram the pairing of these chromosomes in prophase I.
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Ch. 10 - Eukaryotic Chromosome Abnormalities and Molecular Organization
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172
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Table of contents
- Ch. 1 - The Molecular Basis of Heredity, Variation, and Evolution64
- Ch. 2 - Transmission Genetics144
- Ch. 3 - Cell Division and Chromosome Heredity81
- Ch. 4 - Gene Interaction87
- Ch. 5 - Genetic Linkage and Mapping in Eukaryotes103
- Ch. 6 - Genetic Analysis and Mapping in Bacteria and Bacteriophages73
- Ch. 7 - DNA Structure and Replication71
- Ch. 8 - Molecular Biology of Transcription and RNA Processing79
- Ch. 9 - The Molecular Biology of Translation110
- Ch. 10 - Eukaryotic Chromosome Abnormalities and Molecular Organization100
- Ch. 11 - Gene Mutation, DNA Repair, and Homologous Recombination86
- Ch. 12 - Regulation of Gene Expression in Bacteria and Bacteriophage90
- Ch. 13 - Regulation of Gene Expression in Eukaryotes38
- Ch. 14 - Analysis of Gene Function via Forward Genetics and Reverse Genetics72
- Ch. 15 - Recombinant DNA Technology and Its Applications69
- Ch. 16 - Genomics: Genetics from a Whole-Genome Perspective49
- Ch. 17 - Organelle Inheritance and the Evolution of Organelle Genomes27
- Ch. 18 - Developmental Genetics43
- Ch. 19 - Genetic Analysis of Quantitative Traits66
- Ch. 20 - Population Genetics and Evolution at the Population, Species, and Molecular Levels105
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172Not the one you use?Change textbook
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Sanders 3rd EditionCh. 10 - Eukaryotic Chromosome Abnormalities and Molecular OrganizationProblem 13d
Sanders 3rd EditionCh. 10 - Eukaryotic Chromosome Abnormalities and Molecular OrganizationProblem 13dChapter 10, Problem 13d
An animal heterozygous for a reciprocal balanced translocation has the following chromosomes:
MN • OPQRST
MN • OPQRjkl
cdef • ghijkl
cdef • ghiST
Identify the gametes produced by adjacent-2 segregation. Which if any of these gametes are viable?
Verified step by step guidance1
Understand the problem: The animal is heterozygous for a reciprocal balanced translocation, meaning two non-homologous chromosomes have exchanged segments. The goal is to identify the gametes produced by adjacent-2 segregation and determine their viability.
Recall the concept of adjacent-2 segregation: This type of segregation occurs during meiosis when homologous centromeres (from the same chromosome pair) move to the same pole, leading to gametes that contain both translocated and non-translocated chromosomes from the same set.
Analyze the chromosome pairs: The given chromosomes are MN • OPQRST, MN • OPQRjkl, cdef • ghijkl, and cdef • ghiST. Adjacent-2 segregation will result in gametes that combine one chromosome from each homologous pair, but centromeres from the same pair move together.
Determine the gametes: By pairing chromosomes based on adjacent-2 segregation, the gametes will be: (1) MN • OPQRST and cdef • ghijkl, (2) MN • OPQRjkl and cdef • ghiST. These combinations result in unbalanced gametes because they contain duplications and deletions of genetic material.
Assess viability: Gametes with duplications and deletions are typically inviable because they disrupt the balance of genetic material necessary for normal development. Therefore, none of the gametes produced by adjacent-2 segregation are likely to be viable.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Reciprocal Balanced Translocation
A reciprocal balanced translocation occurs when two non-homologous chromosomes exchange segments without any loss of genetic material. This results in a rearrangement of genes but maintains the overall genetic balance. In heterozygous individuals, one chromosome carries the normal gene arrangement while the other has the rearranged segments, which can affect gamete formation and viability.
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12:42
Reciprocal Translocation
Adjacent-2 Segregation
Adjacent-2 segregation is a type of chromosomal segregation that occurs during meiosis in individuals with translocations. In this process, two homologous chromosomes with translocations segregate together, leading to gametes that contain both segments from one chromosome and none from the other. This can result in gametes with unbalanced genetic content, often leading to non-viable offspring.
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12:42Reciprocal Translocation
Gamete Viability
Gamete viability refers to the ability of gametes to develop into a viable organism after fertilization. In the context of adjacent-2 segregation, the gametes produced may have an unbalanced set of chromosomes, which typically results in non-viable zygotes. Understanding which gametes are viable is crucial for predicting the potential outcomes of fertilization in individuals with chromosomal abnormalities.
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21:21Gamete Development
Related Practice
Textbook Question
An animal heterozygous for a reciprocal balanced translocation has the following chromosomes:
MN • OPQRST
MN • OPQRjkl
cdef • ghijkl
cdef • ghiST
Identify the gametes produced by alternate segregation. Which, if any, of these gametes are viable?
518
views
Textbook Question
An animal heterozygous for a reciprocal balanced translocation has the following chromosomes:
MN • OPQRST
MN • OPQRjkl
cdef • ghijkl
cdef • ghiST
Identify the gametes produced by adjacent-1 segregation. Which, if any, of these gametes are viable?
497
views
Textbook Question
An animal heterozygous for a reciprocal balanced translocation has the following chromosomes:
MN • OPQRST
MN • OPQRjkl
cdef • ghijkl
cdef • ghiST
Among the three segregation patterns, which is least likely to occur? Why?
415
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Textbook Question
Dr. Ara B. Dopsis has an idea he thinks will be a boon to agriculture. He wants to create the 'pomato,' a hybrid between a tomato (Lycopersicon esculentum) that has 12 chromosomes and a potato (Solanum tuberosum) that has 48 chromosomes. Dr. Dopsis is hoping his new pomato will have tuber growth like a potato and the fruit production of a tomato. He joins a haploid gamete from each species to form a hybrid and then induces doubling of chromosome number. How many chromosomes will the hybrid have before chromosome doubling?
425
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Textbook Question
Dr. Ara B. Dopsis has an idea he thinks will be a boon to agriculture. He wants to create the 'pomato,' a hybrid between a tomato (Lycopersicon esculentum) that has 12 chromosomes and a potato (Solanum tuberosum) that has 48 chromosomes. Dr. Dopsis is hoping his new pomato will have tuber growth like a potato and the fruit production of a tomato. He joins a haploid gamete from each species to form a hybrid and then induces doubling of chromosome number. Will this hybrid be infertile?
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