An animal heterozygous for a reciprocal balanced translocation has the following chromosomes:
MN • OPQRST
MN • OPQRjkl
cdef • ghijkl
cdef • ghiST
Among the three segregation patterns, which is least likely to occur? Why?

Sanders 3rd Edition
Ch. 10 - Eukaryotic Chromosome Abnormalities and Molecular Organization
Problem 14c
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An animal heterozygous for a reciprocal balanced translocation has the following chromosomes:
MN • OPQRST
MN • OPQRjkl
cdef • ghijkl
cdef • ghiST
Among the three segregation patterns, which is least likely to occur? Why?
Dr. Ara B. Dopsis has an idea he thinks will be a boon to agriculture. He wants to create the 'pomato,' a hybrid between a tomato (Lycopersicon esculentum) that has 12 chromosomes and a potato (Solanum tuberosum) that has 48 chromosomes. Dr. Dopsis is hoping his new pomato will have tuber growth like a potato and the fruit production of a tomato. He joins a haploid gamete from each species to form a hybrid and then induces doubling of chromosome number. How many chromosomes will the hybrid have before chromosome doubling?
Dr. Ara B. Dopsis has an idea he thinks will be a boon to agriculture. He wants to create the 'pomato,' a hybrid between a tomato (Lycopersicon esculentum) that has 12 chromosomes and a potato (Solanum tuberosum) that has 48 chromosomes. Dr. Dopsis is hoping his new pomato will have tuber growth like a potato and the fruit production of a tomato. He joins a haploid gamete from each species to form a hybrid and then induces doubling of chromosome number. Will this hybrid be infertile?
Dr. Ara B. Dopsis has an idea he thinks will be a boon to agriculture. He wants to create the 'pomato,' a hybrid between a tomato (Lycopersicon esculentum) that has 12 chromosomes and a potato (Solanum tuberosum) that has 48 chromosomes. Dr. Dopsis is hoping his new pomato will have tuber growth like a potato and the fruit production of a tomato. He joins a haploid gamete from each species to form a hybrid and then induces doubling of chromosome number.
Can Dr. Dopsis be sure the polyploid will have the characteristics he wants? Why or why not?
A normal chromosome and its homolog carrying a paracentric inversion are shown here. The dot (·) represents the centromere.
Normal ABC • DEFGHIJK
Inversion abc • djihgfe
Diagram the alignment of chromosomes during prophase I.
A normal chromosome and its homolog carrying a paracentric inversion are shown here. The dot (·) represents the centromere.
Normal ABC • DEFGHIJK
Inversion abc • djihgfe
Assume a crossover takes place in the region between F and G. Identify the gametes that are formed following this crossover, and indicate which, if any, gametes are viable.