Textbook Question
For bacteria that are F⁺, Hfr, F', and F⁻, perform or answer the following.
Describe a "partial diploid" and how it originates.
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Ch. 6 - Genetic Analysis and Mapping in Bacteria and Bacteriophages
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172
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Table of contents
- Ch. 1 - The Molecular Basis of Heredity, Variation, and Evolution64
- Ch. 2 - Transmission Genetics144
- Ch. 3 - Cell Division and Chromosome Heredity81
- Ch. 4 - Gene Interaction87
- Ch. 5 - Genetic Linkage and Mapping in Eukaryotes103
- Ch. 6 - Genetic Analysis and Mapping in Bacteria and Bacteriophages73
- Ch. 7 - DNA Structure and Replication71
- Ch. 8 - Molecular Biology of Transcription and RNA Processing79
- Ch. 9 - The Molecular Biology of Translation110
- Ch. 10 - Eukaryotic Chromosome Abnormalities and Molecular Organization100
- Ch. 11 - Gene Mutation, DNA Repair, and Homologous Recombination86
- Ch. 12 - Regulation of Gene Expression in Bacteria and Bacteriophage90
- Ch. 13 - Regulation of Gene Expression in Eukaryotes38
- Ch. 14 - Analysis of Gene Function via Forward Genetics and Reverse Genetics72
- Ch. 15 - Recombinant DNA Technology and Its Applications69
- Ch. 16 - Genomics: Genetics from a Whole-Genome Perspective49
- Ch. 17 - Organelle Inheritance and the Evolution of Organelle Genomes27
- Ch. 18 - Developmental Genetics43
- Ch. 19 - Genetic Analysis of Quantitative Traits66
- Ch. 20 - Population Genetics and Evolution at the Population, Species, and Molecular Levels105
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172Not the one you use?Change textbook
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Sanders 3rd EditionCh. 6 - Genetic Analysis and Mapping in Bacteria and BacteriophagesProblem A.2c
Sanders 3rd EditionCh. 6 - Genetic Analysis and Mapping in Bacteria and BacteriophagesProblem A.2cChapter 6, Problem A.2c
Go online to the Online Mendelian Inheritance of Man (OMIM) website. Look up the following genetic conditions and answer the questions posed about them.
Look up cystic fibrosis (CF), OMIM 602421, and give the gene name and abbreviation and the chromosome location of the gene.
Verified step by step guidance1
Go to the OMIM website at https://omim.org/ to access the Online Mendelian Inheritance in Man database.
In the search bar, enter the OMIM number '602421' or the term 'cystic fibrosis' to find the specific entry for cystic fibrosis.
Once on the cystic fibrosis page, locate the section that lists the gene associated with the condition. This will include the gene name and its standard abbreviation.
Find the chromosome location information, which is usually given as the chromosome number and the specific band or region where the gene is located.
Record the gene name, abbreviation, and chromosome location as your answer to the question.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Online Mendelian Inheritance in Man (OMIM) Database
OMIM is a comprehensive, authoritative online catalog of human genes and genetic disorders. It provides detailed information about gene functions, mutations, and associated phenotypes, making it a vital resource for genetic research and clinical reference.
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Diploid Genetics
Gene Nomenclature and Abbreviations
Genes are identified by standardized names and abbreviations to ensure clear communication. For example, the cystic fibrosis gene is known as CFTR, which stands for Cystic Fibrosis Transmembrane Conductance Regulator, facilitating consistent referencing across studies.
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Chromosomal Location of Genes
Each gene is located on a specific chromosome at a defined position, which is crucial for understanding inheritance patterns and genetic mapping. The chromosomal location helps link genes to diseases and guides genetic testing and research.
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Related Practice
Textbook Question
The flow diagram identifies relationships between bacterial strains in various F factor states. For each of the four arrows in the diagram, provide a description of the events involved in the transition.
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Textbook Question
Go online to the Online Mendelian Inheritance of Man (OMIM) website. Look up the following genetic conditions and answer the questions posed about them.
Go to the 'Molecular Genetics' section and describe the most common mutation of the CF gene.
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Textbook Question
Go online to the Online Mendelian Inheritance of Man (OMIM) website. Look up the following genetic conditions and answer the questions posed about them.
Look up Tay–Sachs disease (TSD), OMIM number 272800, and give the name and abbreviation of the affected gene and the chromosome location of the gene.
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Textbook Question
Go online to the Online Mendelian Inheritance of Man (OMIM) website. Look up the following genetic conditions and answer the questions posed about them.
Go to the 'Population Genetics' section discussing the TSD gene. In a few sentences, summarize the human population in which TSD is most frequently found and give the approximate frequency of heterozygous carriers for the TSD mutation in North American Jews.
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Textbook Question
Conjugation between an Hfr cell and an F⁻ cell does not usually result in conversion of exconjugants to the donor state. Occasionally, however, the result of this conjugation is two Hfr cells. Explain how this occurs.
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