Here are the essential concepts you must grasp in order to answer the question correctly.
Ammonia Toxicity
Ammonia (NH₃) is a byproduct of protein metabolism and is highly toxic to cells. In its ionized form, ammonium (NH₄⁺) can disrupt cellular functions and lead to neurological damage. Therefore, the body must convert ammonia into less toxic substances for safe excretion.
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Urea Cycle
The urea cycle is a series of biochemical reactions that occur primarily in the liver, converting ammonia into urea. This process involves several enzymes and intermediates, ultimately producing urea, which is far less toxic and can be easily excreted by the kidneys in urine.
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Nitrogen Excretion
Nitrogen excretion is a crucial metabolic process for removing excess nitrogen from the body, primarily derived from amino acid breakdown. Urea serves as the main nitrogenous waste product in mammals, allowing for efficient elimination of nitrogen while conserving water compared to other forms like ammonia.
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