Textbook Question
Caprylic acid, CH3 ― (CH2)6 ― COOH, is a C8 fatty acid found in milk.
a. State the number of β oxidation cycles for the complete oxidation of caprylic acid.
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24. Lipid Metabolism
Total Energy from Fatty Acids
1:26 minutesProblem 74a
Textbook Question
Arachidic acid is a C20 fatty acid found in peanut and fish oils.
a. How many cycles of β oxidation are needed for the complete oxidation of arachidic acid?
Verified step by step guidance1
Determine the number of carbon atoms in arachidic acid. The problem states that arachidic acid is a C₂₀ fatty acid, meaning it contains 20 carbon atoms.
Recall that each cycle of β-oxidation removes a two-carbon acetyl-CoA unit from the fatty acid chain. This means the number of cycles required is determined by dividing the total number of carbon atoms by 2 and then subtracting 1 (since the final two-carbon unit does not require an additional cycle).
Set up the calculation: \( \text{Number of cycles} = \frac{\text{Total carbon atoms}}{2} - 1 \). For arachidic acid, substitute 20 for the total carbon atoms: \( \text{Number of cycles} = \frac{20}{2} - 1 \).
Simplify the expression: First, divide 20 by 2 to determine the number of two-carbon units, then subtract 1 to account for the final acetyl-CoA unit that does not require a separate cycle.
The result of this calculation will give you the total number of β-oxidation cycles required for the complete oxidation of arachidic acid.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Beta Oxidation
Beta oxidation is a metabolic process that breaks down fatty acids into acetyl-CoA units, which can then enter the citric acid cycle for energy production. Each cycle of beta oxidation shortens the fatty acid chain by two carbon atoms, releasing energy in the form of ATP. Understanding this process is crucial for determining how many cycles are needed to fully oxidize a fatty acid like arachidic acid.
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Fatty Acid Structure
Fatty acids are carboxylic acids with long hydrocarbon chains, and their structure determines how they are metabolized. Arachidic acid, specifically, is a saturated fatty acid with 20 carbon atoms. Recognizing the number of carbon atoms in a fatty acid is essential for calculating the number of beta oxidation cycles required for its complete oxidation.
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Energy Yield from Fatty Acids
The complete oxidation of fatty acids yields significant amounts of energy, primarily in the form of ATP. Each cycle of beta oxidation produces one FADH2 and one NADH, which are then used in the electron transport chain to generate ATP. Knowing the energy yield from each cycle helps in understanding the overall energy production from the oxidation of arachidic acid.
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