Textbook Question
What metabolic substrate(s) are produced from the carbon atoms of each of the following amino acids?
c. tyrosine
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25. Protein and Amino Acid Metabolism
Amino Acid Catabolism: Carbon Atoms
3:05 minutesProblem 62c
Textbook Question
Name the metabolic substrate(s) that can be produced from the carbon atoms of each of the following amino acids:
c. cysteine
Verified step by step guidance1
Understand that amino acids can be metabolized into various substrates depending on their structure and the metabolic pathways involved. Cysteine is a sulfur-containing amino acid.
Recognize that cysteine can be converted into pyruvate, a key intermediate in cellular metabolism, through a series of enzymatic reactions. Pyruvate is involved in glycolysis and the citric acid cycle.
Note that the sulfur atom in cysteine is removed during its conversion to pyruvate. This process involves desulfuration, where the sulfur is released as hydrogen sulfide (H₂S) or incorporated into other sulfur-containing compounds.
Consider that cysteine can also contribute to the synthesis of glutathione, an important antioxidant in the body, but this is not directly related to the carbon atoms being converted into metabolic substrates.
Summarize that the primary metabolic substrate produced from the carbon atoms of cysteine is pyruvate, which can then enter various metabolic pathways such as energy production or gluconeogenesis.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Amino Acid Metabolism
Amino acid metabolism involves the biochemical processes that break down amino acids for energy or convert them into other compounds. Each amino acid can be transformed into various metabolic substrates, depending on its structure and the body's needs. Understanding these pathways is crucial for identifying the specific substrates produced from amino acids like cysteine.
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Cysteine Catabolism
Cysteine is a sulfur-containing amino acid that can be catabolized to produce several important metabolites. It can be converted into pyruvate, which enters the citric acid cycle for energy production, or into other compounds like glutathione, a key antioxidant. Recognizing these pathways is essential for determining the metabolic substrates derived from cysteine.
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Metabolic Substrates
Metabolic substrates are the molecules that serve as the starting materials for metabolic reactions. In the context of amino acids, these substrates can include intermediates like pyruvate, acetyl-CoA, or other compounds that enter various metabolic pathways. Identifying the specific substrates produced from cysteine is important for understanding its role in metabolism and energy production.
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