Many pharmaceuticals are marketed with the designation "HCl" appended to the name of the drug. What does the "HCl" mean? What type of reaction would be involved in converting a drug to the HCl form? What are the advantages of this form of the drug?
Table of contents
- 1. Matter and Measurements4h 31m
- What is Chemistry?7m
- The Scientific Method9m
- Classification of Matter16m
- States of Matter8m
- Physical & Chemical Changes19m
- Chemical Properties8m
- Physical Properties5m
- Intensive vs. Extensive Properties13m
- Temperature (Simplified)9m
- Scientific Notation13m
- SI Units (Simplified)5m
- Metric Prefixes24m
- Significant Figures (Simplified)11m
- Significant Figures: Precision in Measurements7m
- Significant Figures: In Calculations19m
- Conversion Factors (Simplified)15m
- Dimensional Analysis22m
- Density12m
- Specific Gravity9m
- Density of Geometric Objects19m
- Density of Non-Geometric Objects9m
- 2. Atoms and the Periodic Table5h 23m
- The Atom (Simplified)9m
- Subatomic Particles (Simplified)12m
- Isotopes17m
- Ions (Simplified)22m
- Atomic Mass (Simplified)17m
- Atomic Mass (Conceptual)12m
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- Periodic Table: Representative Elements & Transition Metals7m
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- Law of Definite Proportions9m
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- Wavelength and Frequency (Simplified)5m
- Electromagnetic Spectrum (Simplified)11m
- Bohr Model (Simplified)9m
- Emission Spectrum (Simplified)3m
- Electronic Structure4m
- Electronic Structure: Shells5m
- Electronic Structure: Subshells4m
- Electronic Structure: Orbitals11m
- Electronic Structure: Electron Spin3m
- Electronic Structure: Number of Electrons4m
- The Electron Configuration (Simplified)22m
- Electron Arrangements5m
- The Electron Configuration: Condensed4m
- The Electron Configuration: Exceptions (Simplified)12m
- Ions and the Octet Rule9m
- Ions and the Octet Rule (Simplified)8m
- Valence Electrons of Elements (Simplified)5m
- Lewis Dot Symbols (Simplified)7m
- Periodic Trend: Metallic Character4m
- Periodic Trend: Atomic Radius (Simplified)7m
- 3. Ionic Compounds2h 18m
- Periodic Table: Main Group Element Charges12m
- Periodic Table: Transition Metal Charges6m
- Periodic Trend: Ionic Radius (Simplified)5m
- Periodic Trend: Ranking Ionic Radii8m
- Periodic Trend: Ionization Energy (Simplified)9m
- Periodic Trend: Electron Affinity (Simplified)8m
- Ionic Bonding6m
- Naming Monoatomic Cations6m
- Naming Monoatomic Anions5m
- Polyatomic Ions25m
- Naming Ionic Compounds11m
- Writing Formula Units of Ionic Compounds7m
- Naming Ionic Hydrates6m
- Naming Acids18m
- 4. Molecular Compounds2h 18m
- Covalent Bonds6m
- Naming Binary Molecular Compounds6m
- Molecular Models4m
- Bonding Preferences6m
- Lewis Dot Structures: Neutral Compounds (Simplified)8m
- Multiple Bonds4m
- Multiple Bonds (Simplified)6m
- Lewis Dot Structures: Multiple Bonds10m
- Lewis Dot Structures: Ions (Simplified)8m
- Lewis Dot Structures: Exceptions (Simplified)12m
- Resonance Structures (Simplified)5m
- Valence Shell Electron Pair Repulsion Theory (Simplified)4m
- Electron Geometry (Simplified)8m
- Molecular Geometry (Simplified)11m
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- Dipole Moment (Simplified)15m
- Molecular Polarity (Simplified)7m
- 5. Classification & Balancing of Chemical Reactions3h 17m
- Chemical Reaction: Chemical Change5m
- Law of Conservation of Mass5m
- Balancing Chemical Equations (Simplified)13m
- Solubility Rules16m
- Molecular Equations18m
- Types of Chemical Reactions12m
- Complete Ionic Equations18m
- Calculate Oxidation Numbers15m
- Redox Reactions17m
- Spontaneous Redox Reactions8m
- Balancing Redox Reactions: Acidic Solutions17m
- Balancing Redox Reactions: Basic Solutions17m
- Balancing Redox Reactions (Simplified)13m
- Galvanic Cell (Simplified)16m
- 6. Chemical Reactions & Quantities2h 27m
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- Nature of Energy6m
- First Law of Thermodynamics7m
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- Bond Energy14m
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- Thermal Equilibrium (Simplified)8m
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- Energy Diagrams12m
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- The Equilibrium Constant14m
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- Solubility Product Constant (Ksp)17m
- Spontaneous Reaction10m
- Entropy (Simplified)9m
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- 8. Gases, Liquids and Solids3h 25m
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- Chemistry Gas Laws16m
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- Standard Temperature and Pressure14m
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- Gas Stoichiometry18m
- Intermolecular Forces (Simplified)19m
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- Atomic, Ionic and Molecular Solids10m
- Heating and Cooling Curves30m
- 9. Solutions4h 10m
- Solutions6m
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- Solutions: Mass Percent6m
- Percent Concentrations10m
- Molarity18m
- Osmolarity15m
- Parts per Million (ppm)13m
- Solubility: Temperature Effect8m
- Intro to Henry's Law4m
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- Dilutions12m
- Solution Stoichiometry14m
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- Equivalents11m
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- The Colligative Properties15m
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- 10. Acids and Bases3h 29m
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- Acid and Base Strength17m
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- The pH Scale19m
- Auto-Ionization9m
- pH of Strong Acids and Bases9m
- Acid-Base Equivalents14m
- Acid-Base Reactions7m
- Gas Evolution Equations (Simplified)6m
- Ionic Salts (Simplified)23m
- Buffers25m
- Henderson-Hasselbalch Equation16m
- Strong Acid Strong Base Titrations (Simplified)10m
- 11. Nuclear Chemistry56m
- BONUS: Lab Techniques and Procedures1h 38m
- BONUS: Mathematical Operations and Functions47m
- 12. Introduction to Organic Chemistry1h 34m
- 13. Alkenes, Alkynes, and Aromatic Compounds2h 12m
- 14. Compounds with Oxygen or Sulfur1h 6m
- 15. Aldehydes and Ketones1h 1m
- 16. Carboxylic Acids and Their Derivatives1h 11m
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- 18. Amino Acids and Proteins1h 51m
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- 20. Carbohydrates1h 41m
- Intro to Carbohydrates4m
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- Fischer Projections4m
- Enantiomers vs Diastereomers8m
- D vs L Enantiomers8m
- Cyclic Hemiacetals8m
- Intro to Haworth Projections4m
- Cyclic Structures of Monosaccharides11m
- Mutarotation4m
- Reduction of Monosaccharides10m
- Oxidation of Monosaccharides7m
- Glycosidic Linkage14m
- Disaccharides7m
- Polysaccharides2m
- 21. The Generation of Biochemical Energy2h 8m
- 22. Carbohydrate Metabolism2h 22m
- 23. Lipids2h 26m
- Intro to Lipids6m
- Fatty Acids25m
- Physical Properties of Fatty Acids6m
- Waxes4m
- Triacylglycerols12m
- Triacylglycerol Reactions: Hydrogenation8m
- Triacylglycerol Reactions: Hydrolysis13m
- Triacylglycerol Reactions: Oxidation7m
- Glycerophospholipids15m
- Sphingomyelins13m
- Steroids15m
- Cell Membranes7m
- Membrane Transport10m
- 24. Lipid Metabolism1h 45m
- 25. Protein and Amino Acid Metabolism1h 37m
- 26. Nucleic Acids and Protein Synthesis2h 54m
- Intro to Nucleic Acids4m
- Nitrogenous Bases16m
- Nucleoside and Nucleotide Formation9m
- Naming Nucleosides and Nucleotides13m
- Phosphodiester Bond Formation7m
- Primary Structure of Nucleic Acids11m
- Base Pairing10m
- DNA Double Helix6m
- Intro to DNA Replication20m
- Steps of DNA Replication11m
- Types of RNA10m
- Overview of Protein Synthesis4m
- Transcription: mRNA Synthesis9m
- Processing of pre-mRNA5m
- The Genetic Code6m
- Introduction to Translation7m
- Translation: Protein Synthesis18m
5. Classification & Balancing of Chemical Reactions
Molecular Equations
Problem 20
Textbook Question
An aqueous solution of a cation (represented as blue spheres in the diagram) is allowed to mix with a solution of an anion (represented as green spheres) and the following result is obtained:

Which combinations of cation and anion, chosen from the following lists, are compatible with the observed results? Explain.
Cations: Na+, Ca2+, Ag+, Ni2+
Anions: Cl−, CO23–, CrO42–, NO3–

1
Step 1: Analyze the image provided. The diagram shows two solutions being mixed: one containing green spheres (representing anions) and the other containing red spheres (representing cations). After mixing, a solid precipitate forms at the bottom of the container, indicating that a chemical reaction has occurred and a precipitate has formed.
Step 2: Understand the concept of solubility rules. Precipitation occurs when the product of a reaction between a cation and an anion is insoluble in water. Use solubility rules to determine which combinations of cations and anions can form an insoluble compound.
Step 3: Evaluate the possible combinations of cations and anions provided in the problem. The cations are Na+, Ca2+, Ag+, and Ni2+, and the anions are Cl−, CO3^2−, CrO4^2−, and NO3−. Cross-reference these ions with solubility rules to identify which combinations produce an insoluble compound.
Step 4: Apply solubility rules to each combination. For example, Ag+ often forms insoluble compounds with Cl− (AgCl is insoluble), while Na+ typically forms soluble compounds with all the anions listed. Similarly, Ca2+ can form insoluble compounds with CO3^2− (CaCO3 is insoluble). Continue this process for all combinations.
Step 5: Based on the solubility rules and the observed precipitation in the diagram, identify the specific cation and anion pair that is compatible with the results. Ensure the pair corresponds to an insoluble compound forming a precipitate, as shown in the image.

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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Ionic Compounds
Ionic compounds are formed when cations (positively charged ions) and anions (negatively charged ions) combine due to electrostatic forces. The stability of these compounds depends on the charge and size of the ions involved. In the context of the question, understanding how different cations and anions interact is crucial for predicting which combinations will form stable ionic compounds.
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Solubility Rules
Solubility rules are guidelines that help predict whether an ionic compound will dissolve in water. Certain combinations of cations and anions are known to be soluble or insoluble based on these rules. For example, compounds containing Na+ or NO3− are generally soluble, while others may form precipitates. This concept is essential for determining the compatibility of the given cations and anions.
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Solubility Rules
Precipitation Reactions
Precipitation reactions occur when two solutions containing soluble salts are mixed, resulting in the formation of an insoluble compound that precipitates out of solution. The image illustrates this process, showing layered spheres that suggest a solid formation. Identifying which combinations of cations and anions lead to precipitation is key to answering the question effectively.
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Alcohol Reactions: Dehydration Reactions Concept 1
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