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Multiple Choice
In animal virology, the host range (tropism) of a virus is primarily determined by which factor?
A
The size of the viral capsid and the number of capsomeres
B
The type of nucleic acid (DNA vs. RNA) regardless of host cell receptors
C
Whether the virus has a lipid envelope or is nonenveloped
D
The presence of specific receptors on susceptible host cells and the virus’s ability to enter and replicate in those cells
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Verified step by step guidance
1
Understand that the host range or tropism of a virus refers to the spectrum of host cells or organisms that a virus can infect.
Recognize that the key factor determining host range is the interaction between viral surface proteins and specific receptors on the host cell surface.
Know that the presence of specific receptors on susceptible host cells allows the virus to attach and gain entry, which is essential for infection.
Realize that other factors like the type of nucleic acid, capsid size, or presence of an envelope influence viral structure and replication but do not primarily determine host range.
Conclude that the virus’s ability to enter and replicate inside the host cell, which depends on receptor recognition, is the primary determinant of its host range.