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Multiple Choice
Which of the following erythrocyte disorders is caused by a deficiency of vitamin B12?
A
Hemolytic anemia
B
Sickle cell anemia
C
Polycythemia vera
D
Pernicious anemia
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1
Understand that erythrocyte disorders are conditions affecting red blood cells, often due to deficiencies or genetic mutations.
Recall that vitamin B12 is essential for DNA synthesis in red blood cell production, and its deficiency leads to impaired maturation of erythrocytes.
Identify that Pernicious anemia is a specific type of anemia caused by vitamin B12 deficiency, often due to lack of intrinsic factor needed for B12 absorption.
Recognize that Hemolytic anemia involves premature destruction of red blood cells, Sickle cell anemia is a genetic disorder affecting hemoglobin structure, and Polycythemia vera is a myeloproliferative disorder causing excess red blood cells, none of which are caused by vitamin B12 deficiency.
Conclude that among the options, Pernicious anemia is the erythrocyte disorder caused by vitamin B12 deficiency.