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Multiple Choice
SARS-Cov-2 virus (Covid-19) is a (+) ssRNA virus. Which of the following answers is true about SARS-Cov-2?
A
To replicate the viral genome the replicase enzyme must be transported into the cell within the viral particle.
B
The viral genome can be directly translated by the host cell's ribosomes.
C
The host cell's DNA polymerase is used to replicate the viral genome.
D
The viral genome cannot be directly translated by the host cell's ribosomes and must be modified.
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Verified step by step guidance
1
Understand the nature of SARS-CoV-2: It is a (+) single-stranded RNA virus, meaning its RNA can function directly as mRNA.
Recognize the replication process: (+) ssRNA viruses do not require the replicase enzyme to be transported within the viral particle for initial translation.
Identify the translation mechanism: The viral genome of SARS-CoV-2 can be directly translated by the host cell's ribosomes because it is already in the form of mRNA.
Clarify the role of host cell enzymes: Host cell's DNA polymerase is not involved in the replication of RNA viruses like SARS-CoV-2; RNA-dependent RNA polymerase is used instead.
Evaluate the statement about genome modification: Since the viral genome is (+) ssRNA, it does not need modification to be translated by host ribosomes.