__________ RNA and __________ RNA are antisense; that is, they are complementary to another nucleic acid molecule.
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Understand the terms: Antisense RNA and sense RNA refer to strands of nucleic acids where antisense RNA is complementary to the sense RNA strand or another nucleic acid molecule.
Recall that in molecular biology, messenger RNA (mRNA) carries the genetic code from DNA to the ribosome for protein synthesis, and it is considered the 'sense' strand because it has the same sequence as the DNA coding strand (except for uracil replacing thymine).
Recognize that the antisense RNA is complementary to the mRNA and can bind to it, regulating its function or stability.
Identify that the two types of RNA that are antisense to each other are 'messenger RNA (mRNA)' and 'antisense RNA'.
Therefore, the blanks in the sentence should be filled with 'messenger' for the first blank and 'antisense' for the second blank, indicating that messenger RNA and antisense RNA are complementary to each other.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Antisense RNA
Antisense RNA is a strand of RNA that is complementary to a specific messenger RNA (mRNA) sequence. It binds to the mRNA, preventing translation into protein by blocking ribosome access or promoting degradation.
mRNA carries the genetic code from DNA to the ribosome, where it directs protein synthesis. It is a sense strand, meaning its sequence corresponds to the codons that specify amino acids.
Complementarity refers to the specific base pairing between nucleic acid strands, such as adenine pairing with uracil in RNA and cytosine pairing with guanine. This property allows antisense RNA to bind precisely to its target mRNA.