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Ch. 16 - Adaptive Immunity
Bauman - Microbiology with Diseases by Taxonomy 6th Edition
Bauman6th EditionMicrobiology with Diseases by TaxonomyISBN: 9780134832302Not the one you use?Change textbook
Chapter 16, Problem 4

Mark each statement as either true or false. Rewrite false statements to make them true by changing the underlined words.
__________ Cytotoxic T cells secrete immunoglobulin.

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1
Understand the role of Cytotoxic T cells: Cytotoxic T cells (also called CD8+ T cells) are primarily responsible for killing infected or cancerous cells, not for secreting antibodies.
Recall what secretes immunoglobulins: Immunoglobulins (antibodies) are secreted by B cells, specifically plasma cells, which are differentiated B cells.
Evaluate the statement: The statement 'Cytotoxic T cells secrete immunoglobulin' is false because Cytotoxic T cells do not secrete immunoglobulins.
Rewrite the false statement to make it true by replacing 'Cytotoxic T cells' with 'B cells' or 'Plasma cells': 'B cells secrete immunoglobulin.' or 'Plasma cells secrete immunoglobulin.'
Confirm the corrected statement aligns with immunology concepts: B cells/plasma cells produce antibodies, while Cytotoxic T cells kill infected cells.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Cytotoxic T Cells Function

Cytotoxic T cells (CD8+ T cells) are immune cells that kill infected or cancerous cells by releasing perforin and granzymes, not by secreting antibodies. Their primary role is cell-mediated immunity, targeting cells presenting abnormal antigens.
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Functions of Cytotoxic T Cells (Tc)

Immunoglobulins (Antibodies)

Immunoglobulins are antibodies produced by B cells and plasma cells, not T cells. They recognize and bind specific antigens to neutralize pathogens or mark them for destruction by other immune cells.
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Differences Between T Cells and B Cells

T cells and B cells are lymphocytes with distinct functions: T cells mediate cellular immunity, while B cells produce antibodies for humoral immunity. Understanding their roles clarifies why cytotoxic T cells do not secrete immunoglobulins.
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Regulatory T Cells