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Ch. 16 - Adaptive Immunity
Bauman - Microbiology with Diseases by Taxonomy 6th Edition
Bauman6th EditionMicrobiology with Diseases by TaxonomyISBN: 9780134832302Not the one you use?Change textbook
Chapter 16, Problem 7

The major class of immunoglobulin found on the surfaces of the walls of the intestines and airways is secretory:
a. IgG
b. IgM
c. IgA
d. IgE
e. IgD

Verified step by step guidance
1
Understand that immunoglobulins (antibodies) are proteins produced by B cells that play key roles in immune defense, each class having distinct functions and locations.
Recall the main classes of immunoglobulins: IgG, IgM, IgA, IgE, and IgD, and their typical roles in the immune system.
Focus on the immunoglobulin class that is predominantly found in mucosal areas such as the intestines and airways, where it provides a first line of defense by neutralizing pathogens.
Identify that secretory immunoglobulin A (IgA) is the major antibody class present on mucosal surfaces, including the walls of the intestines and airways.
Conclude that the correct answer is the immunoglobulin class known as secretory IgA, which is specialized for mucosal immunity.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Immunoglobulin Classes

Immunoglobulins (antibodies) are proteins produced by B cells that recognize and neutralize pathogens. The main classes include IgG, IgA, IgM, IgE, and IgD, each with distinct roles in immune defense and distribution in the body.
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Review Table of Immunoglobin Classes

Secretory IgA and Mucosal Immunity

Secretory IgA is the predominant antibody found on mucosal surfaces such as the intestines and airways. It plays a critical role in protecting mucous membranes by preventing pathogen adherence and neutralizing toxins without causing inflammation.
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Functions of Other Immunoglobulins

IgG is the most abundant antibody in blood and extracellular fluid, providing systemic immunity. IgM is the first antibody produced during an immune response. IgE is involved in allergic reactions, and IgD functions mainly as a B cell receptor.
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Functional Groups