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Multiple Choice
Which of the following is a component of the juxtaglomerular apparatus?
A
Podocyte
B
Collecting duct
C
Macula densa
D
Loop of Henle
Verified step by step guidance
1
Understand the juxtaglomerular apparatus (JGA): The JGA is a specialized structure in the kidney that regulates blood pressure and filtration rate in the glomerulus. It consists of three main components: the macula densa, juxtaglomerular cells, and extraglomerular mesangial cells.
Identify the macula densa: The macula densa is a group of specialized epithelial cells located in the distal convoluted tubule, near the glomerulus. These cells sense sodium chloride (NaCl) concentration in the tubular fluid and play a key role in signaling changes in filtration rate.
Eliminate incorrect options: Podocytes are part of the filtration barrier in the glomerulus, not the JGA. The collecting duct is involved in water and electrolyte reabsorption but is not part of the JGA. The Loop of Henle is responsible for creating a concentration gradient in the medulla but is not part of the JGA.
Confirm the correct answer: The macula densa is indeed a component of the juxtaglomerular apparatus, as it plays a critical role in monitoring and regulating kidney function.
Summarize the reasoning: The juxtaglomerular apparatus includes the macula densa, juxtaglomerular cells, and extraglomerular mesangial cells. Among the given options, only the macula densa is part of this structure.