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Multiple Choice
The filtration membrane is created by the ________ and ________.
A
proximal tubule and distal tubule
B
renal capsule and ureter
C
glomerular endothelium and podocytes
D
loop of Henle and collecting duct
Verified step by step guidance
1
Understand the context: The filtration membrane is a critical structure in the nephron of the kidney, responsible for filtering blood to form urine. It is part of the glomerulus, which is the site of filtration in the renal corpuscle.
Identify the components of the filtration membrane: The filtration membrane is composed of three layers: the fenestrated glomerular endothelium, the basement membrane, and the podocytes (specialized epithelial cells).
Clarify the role of the glomerular endothelium: This layer contains fenestrations (small pores) that allow water and small solutes to pass through while preventing the passage of blood cells.
Explain the function of podocytes: Podocytes have foot-like extensions called pedicels that interlock to form filtration slits. These slits further regulate what can pass through the filtration membrane, ensuring that large proteins and cells are retained in the blood.
Conclude by connecting the components: The glomerular endothelium and podocytes work together to form the filtration membrane, which is essential for the selective filtration of blood in the kidney's glomerulus.