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Multiple Choice
Erythromycin interferes with protein synthesis by binding to which ribosomal subunit?
A
50S subunit
B
30S subunit
C
60S subunit
D
40S subunit
Verified step by step guidance
1
Understand the role of ribosomes in protein synthesis: Ribosomes are the cellular structures responsible for translating mRNA into proteins. They consist of two subunits, a larger and a smaller one, which differ between prokaryotes and eukaryotes.
Identify the type of organism: Erythromycin is an antibiotic that targets bacterial cells, which are prokaryotic. Prokaryotic ribosomes are composed of a 50S large subunit and a 30S small subunit.
Recognize the mechanism of action of erythromycin: Erythromycin is known to inhibit protein synthesis by binding to the ribosomal subunit, preventing the elongation of the protein chain.
Determine which subunit erythromycin binds to: Erythromycin specifically binds to the 50S subunit of the bacterial ribosome, blocking the exit tunnel of the ribosome and thus inhibiting protein synthesis.
Eliminate incorrect options: Since erythromycin binds to the 50S subunit, the options 30S, 60S, and 40S can be eliminated as they do not correspond to the subunit targeted by erythromycin in prokaryotic cells.