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Multiple Choice
Which of the following events occurs because of the low pH of the stomach?
A
Absorption of vitamin B12
B
Inhibition of gastric lipase
C
Neutralization of stomach acid
D
Activation of pepsinogen to pepsin
Verified step by step guidance
1
Understand that the stomach has a very acidic environment, with a pH typically around 1.5 to 3.5, which is crucial for its digestive functions.
Recognize that pepsinogen is an inactive enzyme precursor secreted by the stomach lining. It requires activation to become pepsin, an active enzyme that digests proteins.
Identify that the low pH of the stomach is necessary for the conversion of pepsinogen to pepsin. The acidic environment causes a conformational change in pepsinogen, exposing its active site.
Consider that the activation of pepsinogen to pepsin is an essential process for protein digestion, as pepsin breaks down proteins into smaller peptides.
Conclude that the low pH of the stomach is directly responsible for the activation of pepsinogen to pepsin, enabling effective protein digestion.