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Multiple Choice
Which immunoglobulin is found on the surface of B lymphocytes and is important in B cell activation?
A
IgG
B
IgE
C
IgD
D
IgA
Verified step by step guidance
1
Understand the role of B lymphocytes in the immune system: B lymphocytes (B cells) are responsible for producing antibodies and play a crucial role in adaptive immunity. They require activation to initiate antibody production.
Learn about immunoglobulins (antibodies): Immunoglobulins are proteins produced by B cells that help identify and neutralize pathogens. There are five main classes of immunoglobulins: IgG, IgA, IgM, IgE, and IgD, each with distinct functions.
Focus on IgD: IgD is a type of immunoglobulin found on the surface of immature B cells. It plays a critical role in B cell activation by acting as a receptor for antigens, which triggers the B cell to become activated and start producing antibodies.
Compare IgD with other immunoglobulins: IgG is the most abundant antibody in circulation and provides long-term immunity. IgA is found in mucosal areas and secretions like saliva and tears. IgE is involved in allergic responses. None of these are primarily involved in B cell activation like IgD.
Conclude that IgD is the correct answer: Based on its function as a receptor on B cells and its role in activation, IgD is the immunoglobulin associated with B cell activation.