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Multiple Choice
What happens when the concentration of Na+ decreases in the ascending limb of the nephron?
A
The secretion of K+ in the collecting duct decreases.
B
The reabsorption of water in the descending limb increases.
C
The reabsorption of Na+ in the distal convoluted tubule increases.
D
The osmolarity of the medullary interstitium decreases.
Verified step by step guidance
1
Understand the function of the nephron: The nephron is the functional unit of the kidney, responsible for filtering blood and forming urine. It consists of different segments, each with specific roles in reabsorption and secretion.
Identify the role of the ascending limb of the nephron: The ascending limb of the loop of Henle is impermeable to water and actively transports Na+ and Cl- ions out of the tubular fluid into the medullary interstitium, contributing to the osmotic gradient.
Consider the effect of decreased Na+ concentration: If the concentration of Na+ decreases in the ascending limb, less Na+ is transported into the medullary interstitium, which can affect the osmotic gradient.
Analyze the impact on the medullary interstitium: A decrease in Na+ transport leads to a reduction in the osmolarity of the medullary interstitium, as there are fewer solutes to maintain the gradient.
Conclude the physiological outcome: With a decreased osmolarity in the medullary interstitium, the ability to reabsorb water in the collecting duct is affected, but the primary change is the decrease in osmolarity itself.