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Multiple Choice
Which cells are responsible for forming the blood-testis barrier?
A
Spermatogonia
B
Granulosa cells
C
Sertoli cells
D
Leydig cells
Verified step by step guidance
1
Understand the function of the blood-testis barrier: It is a physical barrier in the testis that separates the developing sperm cells from the bloodstream, protecting them from harmful substances and immune responses.
Identify the location and role of Sertoli cells: Sertoli cells are located in the seminiferous tubules of the testis and provide support and nourishment to the developing sperm cells.
Recognize the specific function of Sertoli cells in forming the blood-testis barrier: Sertoli cells create tight junctions between each other, which form the blood-testis barrier, isolating the germ cells from the blood.
Differentiate between the roles of other cell types: Spermatogonia are the germ cells that develop into sperm, granulosa cells are found in the ovaries, and Leydig cells produce testosterone in the testis but do not form the blood-testis barrier.
Conclude that Sertoli cells are responsible for forming the blood-testis barrier due to their unique ability to create tight junctions and provide a protected environment for spermatogenesis.