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Multiple Choice
The afferent arteriole contains cells called ____________ that secrete the enzyme renin.
A
podocytes
B
mesangial cells
C
macula densa cells
D
juxtaglomerular cells
Verified step by step guidance
1
Understand the anatomy of the nephron and its associated structures. The afferent arteriole is a blood vessel that supplies blood to the glomerulus, a key structure in the kidney responsible for filtration.
Learn about the juxtaglomerular apparatus (JGA), which is a specialized structure located near the glomerulus. It plays a critical role in regulating blood pressure and filtration rate in the kidney.
Identify the specific cell types within the JGA. Juxtaglomerular cells are located in the walls of the afferent arteriole and are responsible for secreting the enzyme renin in response to signals such as low blood pressure or low sodium levels.
Differentiate juxtaglomerular cells from other cell types in the nephron, such as podocytes (which are part of the filtration barrier in the glomerulus), mesangial cells (which provide structural support and regulate filtration), and macula densa cells (which sense sodium concentration in the distal tubule).
Conclude that juxtaglomerular cells are the correct answer because they are the specific cells in the afferent arteriole responsible for renin secretion, which is essential for the renin-angiotensin-aldosterone system (RAAS) that regulates blood pressure and fluid balance.