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Multiple Choice
Which of the following is an effect of norepinephrine binding to beta-2 adrenergic receptors?
A
Stimulation of digestive gland secretion
B
Bronchodilation in the lungs
C
Increased heart rate
D
Constriction of blood vessels in the skin
Verified step by step guidance
1
Step 1: Understand the role of norepinephrine in the autonomic nervous system. Norepinephrine is a neurotransmitter and hormone that primarily acts on adrenergic receptors, which are divided into alpha and beta subtypes. Beta-2 adrenergic receptors are specifically involved in smooth muscle relaxation in certain tissues.
Step 2: Learn the physiological effects of beta-2 adrenergic receptor activation. When norepinephrine binds to beta-2 adrenergic receptors, it triggers a signaling cascade that leads to the relaxation of smooth muscles, particularly in the airways and blood vessels.
Step 3: Focus on the lungs. Beta-2 adrenergic receptor activation in the lungs causes bronchodilation, which is the widening of the airways. This effect helps improve airflow and is critical during the 'fight or flight' response.
Step 4: Eliminate incorrect options. Stimulation of digestive gland secretion is not associated with beta-2 adrenergic receptors; it is more related to parasympathetic activity. Increased heart rate is primarily mediated by beta-1 adrenergic receptors, not beta-2. Constriction of blood vessels in the skin is mediated by alpha adrenergic receptors, not beta-2.
Step 5: Conclude that the correct effect of norepinephrine binding to beta-2 adrenergic receptors is bronchodilation in the lungs, as this aligns with the receptor's role in smooth muscle relaxation in the airways.