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Multiple Choice
What happens when a resting neuron's membrane depolarizes?
A
The neuron enters a refractory period.
B
The inside of the neuron becomes less negative compared to the outside.
C
The neuron releases neurotransmitters into the synaptic cleft.
D
The inside of the neuron becomes more negative compared to the outside.
Verified step by step guidance
1
Understand the concept of membrane potential: A resting neuron has a membrane potential, which is the electrical potential difference across its membrane. This is typically around -70 mV, with the inside of the neuron being more negative compared to the outside.
Define depolarization: Depolarization is a change in the membrane potential that makes the inside of the neuron less negative compared to the outside. This occurs when positively charged ions, such as sodium (Na+), enter the neuron.
Identify the effect of depolarization: When a neuron depolarizes, the membrane potential becomes less negative. This means the difference in charge between the inside and outside of the neuron decreases.
Differentiate from other options: The refractory period is a phase following an action potential where the neuron is less responsive to stimuli. Neurotransmitter release occurs when an action potential reaches the synaptic terminal, not during initial depolarization.
Conclude with the correct understanding: During depolarization, the inside of the neuron becomes less negative compared to the outside, which is a key step in the process of generating an action potential.