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Multiple Choice
Which layer of the skin, as seen in a histology slide, contains both stem cells and melanocytes?
A
Stratum granulosum
B
Stratum spinosum
C
Stratum basale
D
Stratum corneum
Verified step by step guidance
1
Understand the structure of the epidermis, which is composed of five layers: stratum basale, stratum spinosum, stratum granulosum, stratum lucidum (only in thick skin), and stratum corneum.
Learn the function of the stratum basale, which is the deepest layer of the epidermis. It is a single layer of cuboidal to columnar cells that sits directly on the basement membrane.
Recognize that the stratum basale contains stem cells, which are responsible for generating new keratinocytes through mitosis. These keratinocytes migrate upward to replenish the layers above.
Understand that melanocytes, the cells responsible for producing melanin (the pigment that gives skin its color), are also located in the stratum basale. Melanin protects the skin from UV radiation damage.
Review histology slides to identify the stratum basale by its position at the base of the epidermis and the presence of both stem cells and melanocytes, distinguishing it from other layers like the stratum spinosum or stratum granulosum.