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Multiple Choice
Which three proteins primarily make up the thin filaments of muscle myofibrils?
A
Actin, tropomyosin, and troponin
B
Troponin, myosin, and nebulin
C
Myosin, actin, and titin
D
Tropomyosin, myosin, and dystrophin
Verified step by step guidance
1
Step 1: Begin by understanding the structure of muscle myofibrils. Myofibrils are composed of repeating units called sarcomeres, which contain thin and thick filaments. Thin filaments are primarily involved in muscle contraction and are made up of specific proteins.
Step 2: Recall the three primary proteins that make up the thin filaments. These proteins are actin, tropomyosin, and troponin. Actin forms the backbone of the thin filament, tropomyosin regulates the binding sites on actin, and troponin is involved in calcium-mediated regulation of muscle contraction.
Step 3: Eliminate incorrect options by identifying proteins that are not part of the thin filaments. For example, myosin is a thick filament protein, titin is involved in sarcomere elasticity, nebulin stabilizes actin filaments, and dystrophin connects the cytoskeleton to the extracellular matrix.
Step 4: Match the correct combination of proteins to the thin filaments. The correct answer is actin, tropomyosin, and troponin, as these are the proteins that primarily make up the thin filaments.
Step 5: Confirm your understanding by reviewing the roles of actin, tropomyosin, and troponin in muscle contraction. Actin provides the structural framework, tropomyosin blocks or exposes binding sites, and troponin interacts with calcium to initiate contraction.